Effects of Materials Based on Acrylic Resines on Inflammatory Markers IL-8 and TGFb1 in Gingival Crevicular Fluid

Materials based on acrylic resins are commonly used in dental practice. These are obtained through various technologies, which determine the chemical, physical and biological properties of the final product, which can influence the inflammatory processes in the periodontal tissue. To evaluate the effects of these materials, we identified the concentrations of TGF beta 1 and IL8 in crevicular fluid in 23 patients with temporary dentures made of polymethyl methacrylate by two polymerization methods: (1) a product processed immediately prior to application, wherein the polymerization of the material occurs in the oral cavity; and (2) a product processed in the dental laboratory from a prepolymerized block (block-type PMMA), and applied directly into the patient's mouth. The results of our study revealed a significant correlation between the IL-8 inflammation marker and the clinical parameters in the periodontal tissue exposed to the polymerization of the material in the oral cavity.