Infectivity of Norovirus GI and GII from Bottled Mineral Water during a Waterborne Outbreak, Spain.

Susana Guix,Cristina Fuentes,Rosa M Pintó,Albert Blanco,Aurora Sabrià,Eduard Anfruns-Estrada,Virginia Rodríguez Garrido,Manuel Alonso,Rosa Bartolomé,Thais Cornejo,Tomàs Pumarola,Albert Bosch

EMERGING INFECTIOUS DISEASES（2020）

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摘要

During a waterborne outbreak of norovirus in Spain, we estimated 50% illness doses for a group of exposed (secretor) persons to be 556 (95% CI 319-957) genome copies/day for norovirus GI and 2,934 (95% CI 1,683-5,044) genome copies/day for norovirus GII. Use of a propidium monoazide viability assay reduced these values.

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关键词

50% illness dose,GI,GII,Spain,bottled mineral water,dose causing illness,genotypes,infectivity,norovirus,real-time quantitative PCR,secretor status,viruses,water cooler,waterborne outbreak

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