P753 Monitoring the evaluation of congenital syphilis cases in the state of são paulo, 2007 to 2017

Background Congenital syphilis (CS) is still considered a public health problem in the state of Sao Paulo, Brazil: 4,039 cases were reported in 2017 -incidence rate = 6.6 per 1,000 live births. The objective of this study was to investigate the evaluation of CS cases in 2007 and 2017 in the state of Sao Paulo. Methods A descriptive study was carried out with the data of national surveillance system in the period 2007 to 2017. Of the following evaluation tests performed the percentage of non-performed and positive results were calculated: - Venereal Disease Research Laboratory (VDRL) on the serum; - long-bone radiography; -cerebrospinal fluid (CSF) for cell count and protein; - CSF for VDRL. Results From 2007 to 2017, 21,524 cases of CS born alive were reported: 743 in 2007 and 3,687 in 2017. The percentage of non-performed and positive tests in 2007 and 2017, and the percentage variation (PV) between the two years were: - non-performed - VDRL on the serum (4.0% and 1.8%, PV = −56.3%), CSF for VDRL (23.4% and 21.4%, PV = −7.1), CSF for cell count and protein (23% and 21,4%: PV = 7,1%), long-bone radiography (13,7% and 9.9%, PV = −27.9%); - positive results - VDRL on the serum (59.1% and 81.1%; PV = 37.3%), CSF for VDRL (1.3% and 3.5%; PV = 157.9%), CSF for cell count and protein (1.6% and 10.1%: PV = 523%), long-bone radiography (2.6% and 3.5%, PV = 36.8%). Conclusion There was an improvement in adherence to the CS evaluation protocol. In addition, we highlight the increase in the percentage of altered tests of children born alive in the period, pointing to the greater severity of the cases, and the need of improving the monitoring of these children in order to reduce the impact of congenital syphilis. Disclosure No significant relationships.