RESLS: Region and Edge Synergetic Level Set Framework for Image Segmentation.

The active contour models with level set evolution have been visited with a vast number of methods for image segmentation. They can be mainly classified into region-based and edge-based models, and it has been validated that the hybrid variants combining both region and edge information can improve the segmentation performance. However, to the best of our knowledge, the theoretical foundation of collaboration mechanism between the region and the edge information is limited. Specifically, most existing hybrid models are just combining all the energy terms together, resulting in great challenges of choosing an appropriate weight coefficient for each term and accommodating different modalities of imaging. To overcome these difficulties, this paper proposes a region and edge synergetic level set framework named RESLS. It provides an approach to construct new hybrid level set models using a normalized intensity indicator function that allows the region information easily embedding into the edge-based model. In this case, the energy weights of region and edge terms can be constrained by the global optimization condition deduced from the framework. Some representative as well as state-of-the-art models are taken as examples to demonstrate the generality of our method. The experiments validate that under the guidance of the optimization condition, the weighting parameter of each term can be reliably chosen. Meanwhile, the segmentation accuracy, robustness, and computational efficiency of RESLS can be improved compared with its component models.