(224) – Concomitant Proteomic and Metabolomic Changes upon LVAD Therapy of Ischemic Cardiomyopathy

J.H. Shahinian,B. Mayer,S. Tholen,M. Schlimpert,B. Kammerer,M. Biniossek, U. Heizmann,F. Rueter,M. Grapow,O. Reuthebuch,F. Eckstein,F. Beyersdorf,M. Siepe,O. Schilling

Journal of Heart and Lung Transplantation（2017）

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摘要

We aimed to investigate the impact of mechanical unloading with a left ventricular assist device (LVAD) on the myocardial proteome and metabolome in non-diabetic patients with ischemic cardiomyopathy and reduced ejection fraction (EF < 20 %).

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关键词

ischemic cardiomyopathy,metabolomic changes,lvad therapy

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