P3.01-005 9 Year's in Oncopathology at a Latin American Country: Demographic and Pathology Characterization of Lung Cancer at National Cancer Institute: Topic: Morphology

This article reviews the pathologic classification of lung cancer based on the WHO classification of lung tumors and the IASLC/ATS/ERS classification in our population, we don’t use 2015-WHO classification because at ongoing of this review wasn’t release yet. Between January 2004 and December 2013, all patients diagnosed with a pathology of SCLC and NSCLC at National Institute of Oncology at Paraguay were analyzed retrospectively. Demographic information were recorded. SPSS 20 was used to analyze. We studied 478 subjects. The histological subtypes found were SCC (Squamous cell carcinoma) : 48.7% and prevalence grade III: 87.3% (P=0.000), Adenocarcinoma: 21%.Prevalence grade II: 50% (P=0.000), Small cell carcinoma 14%, Large cell carcinoma 75 Prevalence grade III: 100% (P=0.000), Unclassified 6% Prevalence grade III:100% (P=0.000), Carcinoid tumors 1.3%, Adenosquamous Carcinoma 0.8%, Carcinomas of salivary gland type 0,8% prevalence grade II: 100% (P=0.000), carcinomas with pleomorphic sarcomatoid or sarcomatous elements 0.5%. Gender prevalence at women was SCC: 37.5% and Squamous cell carcinoma at men: 50.3% (P=0.000), Group ages prevalence 18 to 44 years old: Squamous cell carcinoma 39.1%, 45 to 65: Squamous cell carcinoma 46.3%.>65 years: Squamous cell carcinoma 55.5% (P=0.018). At relation with prevalence at rural area living place SCC: 51.9% and Urban SCC: 43.7% both (P>0.05). First motive of consultation was dyspnea Carcinomas of salivary gland type: 66,7%, carcinomas with pleomorphic sarcomatoid or sarcomatous elements: 50.7%, Small cell carcinoma: 44,4%, Unclassified: 43.5% Large cell carcinoma: 32.0%, Adenocarcinoma: 30%, Adenosquamous Carcinoma: 30.0%. Coug to Carcinoid tumors 40%, SCC: 32.4% (P>0.05). Clinical severity correlation to pathologic classification predominance at stage IV was to carcinomas with pleomorphic sarcomatoid or sarcomatous elements: 100%, Carcinomas of salivary gland type: 100%, Adenocarcinoma: 64,9%,Large Cell Carcinoma 60%, Unclassified: 50%. SCC: 43.7%. At stage IIIB Adenosquamous Carcinoma: 100%, Unclassified: 50%. At IB Carcinoid tumors 50%. Small cell carcinoma advance stage: 69.2% (P=0.000). We found statistical significance relation between severity grade and histopathology of lung cancer also with gender prevalence. We hadn't found statistical significance relation with first motive of consultation or living place. We had statistical relation at our population with age groups as bibliography references mentions that is rare to find lung cancer in young patients, but we found prevalence at 18 to 44 years old of Squamous cell carcinoma at 39.1% in this age group. Also we found statistical relation at histopathology type ad clinical severity stage, in our population IV was predominant. This is the first review of relation between histopathology with clinical and demographic variables in our Institution.