The correlation between the traditional Chinese medicine (TCM) syndrome and the concentration of adiponectin and peroxynitrite in dyslipidemia patients

Abstract Introduction Traditional Chinese medicine (TCM) plays an important role in the treatment of dyslipidemia and it is important to identify an objective index for the TCM syndrome. This study focused on exploring the correlation between TCM syndrome and the serum concentration of adiponectin (APN) and peroxynitrite (ONOO − ) in dyslipidemia patients. Methods Cross-sectional study design was used. Patients with dyslipidemia were assigned with corresponding TCM scores and their APN and ONOO − serum content measured. We also explored the characteristics of APN and ONOO − in different TCM syndromes and their relationship between patient’s TCM scores. Results The results indicated the serum levels of APN and ONOO − were higher for those people with an Excess Syndrome than for those with a Deficiency Syndrome (P  − (r = 0.58, P  − (r = 0.50, P  Conclusions As the serum levels of APN and ONOO − appeared to be correlated with the TCM scores, these parameters could be potentially be used as objective and standardized biomarkers for TCM syndrome differentiation.