Preliminary Assessment of the Motor Activity Log-28 in Patients with Chronic Stroke (P5.174)

OBJECTIVE: Assess if the Motor Activity Log-28 (MAL-28) is a suitable measure to examine the relationship between arm impairment and use in stroke participants enrolled in an arm rehabilitation study. We aimed to 1) determine whether the MAL-28 is a trustworthy self-report measure for characterizing use, and 2) assess whether the MAL-28 is sensitive to impairment change throughout the study.BACKGROUND: Improvements in arm impairment following stroke are evaluated by self-report or clinical measures. The MAL-28 is a stroke-specific self-report questionnaire of arm function that quantifies Amount of Use (AOU) and Quality of Movement (QOM) for daily activities outside the clinic. Previous studies of a modified MAL demonstrated validity of the AOU and QOM scales, but only the QOM scale was reliable.DESIGN/METHODS: Clinical and self-report data were analyzed at baseline, post-therapy, and follow-up. Clinical measures were the Fugl-Meyer (F-M) and Wolf Motor Function Test (WMFT). Self-report measures were the MAL-28 and Stroke Impact Scale (SIS). Participants were stratified by impairment severity. Correlation analyses (Spearman’s ρ) were conducted in the less impaired group (n=9).RESULTS: MAL-28 AOU and QOM scales significantly correlated with established scales (F-M, WMFT, SIS hand domain) at baseline. Baseline F-M scores were strongly correlated with baseline AOU (ρ=0.6889, pu003c0.0132) and QOM scores (ρ=0.7276, pu003c0.0073). Changes in AOU scores were sensitive to changes in SIS physical domain scores (ρ=0.7342, pu003c0.0243). Changes in QOM scores were sensitive to changes in WMFT Functional Ability scores (ρ=0.6245, pu003c0.0722).CONCLUSIONS: MAL-28 was an acceptable self-report measure of baseline ability for less impaired stroke participants. Quality of arm use in a non-clinical setting detected by the MAL-28 was sensitive to qualitative changes assessed by clinical evaluation.Study Supported by: University of Maryland School of Medicine NIA Short-Term Training Program on Aging Grant T35AG036679;VA Department of Research u0026 Development Merit Grant B6935R. Disclosure: Dr. Simpson has nothing to disclose. Dr. Conroy has nothing to disclose. Dr. Bever has nothing to disclose.