Asociación entre adiposidad, inflamación y factores de riesgo cardiovascular en un grupo de escolares mexicanos

objective: To evaluate the differences in inflammation markers and cardiovascular risk factors in a group of school-aged children with and without excessive adiposity. To examine the relationship between adiposity, inflammation, and cardiovascular risk factors. Methods: Cross-sectional study of 285 school children (8-12 years old). Adiposity (body mass index, BMI, total body fat, TBF, and waist circumference), inflammatory markers (C-reactive protein [CRP], interleukin 1β [IL-1β], interleukin 6 [IL-6], and tumor necrosis factor-α [TNF-α]) and cardiovascular risk factors were analyzed. Mean differences were calculated and multiple regression models were made. results: Obese children had higher concentrations of CRP and IL-1β; children with abdominal obesity also had higher CRP levels. A higher BMI was associated with higher blood pressure, and higher total cholesterol, triglycerides-TAG, and insulin concentrations, and with lower HDL-cholesterol. The CRP and IL-1β concentrations correlated significantly with the three adiposity indices. The IL-6 concentrations were associated with TAG, and IL-1β with HDL-cholesterol concentration, after adjustment by BMI.