Osteoporosis in menopause.

Journal of Obstetrics and Gynaecology Canada(2014)

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摘要
To provide guidelines for the health care provider on the prevention, diagnosis, and clinical management of postmenopausal osteoporosis.Strategies for identifying and evaluating high-risk individuals, the use of bone mineral density (BMD) and bone turnover markers in assessing diagnosis and response to management, and recommendations regarding nutrition, physical activity, and the selection of pharmacologic therapy to prevent and manage osteoporosis.Published literature was retrieved through searches of PubMed and The Cochrane Library on August 30 and September 18, 2012, respectively. The strategy included the use of appropriate controlled vocabulary (e.g., oteoporosis, bone density, menopause) and key words (e.g., bone health, bone loss, BMD). Results were restricted to systematic reviews, practice guidelines, randomized and controlled clinical trials, and observational studies published in English or French. The search was limited to the publication years 2009 and following, and updates were incorporated into the guideline to March 2013. Grey (unpublished) literature was identified through searching the websites of health technology assessment and health technology assessment-related agencies, clinical practice guideline collections, clinical trial registries, and national and international medical specialty societies.Abstract available from the publisher.
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关键词
Osteoporosis,prevention,treatment,diagnosis,bone mineral density,dual energy x-ray absorptiometry,bone turnover markers,vertebral fractures,fragility fractures,antiresorptive,hormone therapy,selective estrogen-receptor modulator,bisphosphonates,calcitonin,anabolic,bone forming agent
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