A case of superior sulcus tumor resected after chemoradiotherapy and resulted in complete response]

Hirotsugu Nagase,Hideoki Yokouchi,Kentaro Maruyama, Yoshihito Ide,Hideo Ota, Kazuyuki Okada, Tetsu Yanagisawa, Ryota Mukai,Kohei Murata,Masakatsu Kinuta, Masamitsu Tamai

Gan to kagaku ryoho. Cancer & chemotherapy(2009)

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摘要
We report a case of superior sulcus tumor performed chemoradiation followed by operation obtaining a long-term survival without relapse. A case is a male of fifties, who visited our hospital with the complaint of numbness in the ulnar side of the left arm and scapular pain. Computed tomography revealed a mass, 4 cm in diameter in the apical portion of the left lung extending to superior sulcus and supraclavicular region. The tumor decreased in size by 2 cm after induction chemoradiotherapy under clinical diagnosis of T3N0M0 superior sulcus tumor and then the apex of the lung and the chest wall was resected with some superior mediastinal lymph nodes. No residual viable tumor cells were seen in the resected tissues. He was followed-up by CT without adjuvant therapy and is alive with no sign of relapse 6 years after the operation, so the effect of induction chemoradiotherapy is evaluated to be complete response. Multimodality therapy with induction chemoradiation and surgery for superior sulcus tumor without lymph node metastasis appears promising.
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