Murine Heart Volume: Numerical Comparison and Calibration of Conductance Catheter Models

Biomedical Engineering, IEEE Transactions  (2014)

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摘要
A full set of finite-element method (FEM) studies of the catheter within a cylindrical cuvette and within an elliptical cuvette are presented along with novel insight on the fundamental electromagnetic properties of the catheter. An in vitro experiment with modified small mouse pressure-volume catheters was conducted and the results are presented as a validation of the FEM models. In addition, sensitivity analysis on the electrode size and position is conducted and the results allow for a novel calibration factor based on catheter geometry to be presented. This calibration factor is used in conjunction with Wei's conductance volume equations to reduce the average measured error in cuvette volume measurements from 26.5% to 5%.
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关键词
bioelectric potentials,biomedical electrodes,biomedical measurement,calibration,cardiology,catheters,electric admittance measurement,electromagnetism,finite element analysis,geometry,measurement errors,physiological models,sensitivity analysis,FEM model validation,FEM study,Wei conductance volume equations,average measured error reduction,calibration factor,catheter geometry,conductance catheter model calibration,cuvette volume measurements,cylindrical cuvette,electrode position sensitivity analysis,electrode size sensitivity analysis,electromagnetic properties,elliptical cuvette,finite element method,in vitro experiment,modified small mouse pressure-volume catheters,murine heart volume,numerical comparison,Conductance-based catheter,electromagnetic simulation,finite-element method (FEM),murine heart,pressure??volume,sensitivity analysis,sensor calibration
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