Blood-Glucose Control Of Diabetic Children Eating Un-Refined (U) Or Refined (R), High-Carbohydrate Diets

PEDIATRIC RESEARCH(1980)

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摘要
Increasing the proportion of carbohydrate in diabetic diets may improve diabetic control in adults, but it is unclear whether this is due to the amount or type of carbohydrate eaten. A randomised crossover outpatient study was performed on 6 diabetic children to compare the effect of eating unrefined or refined high carbohydrate diets (50-55%C) from acceptable food sources, on blood glucose control. The unrefined diet used wholefoods such as beans and wholemeal bread (mean fibre:energy ratio 3:100), and the refined diet used processed foods such as white bread (mean fibre:energy ratio 1:100). The diets were individualised and were isocaloric for carbohydrate, lat, and protein. Diabetic control was assessed by daily urinalysis for glucose, home blood glucose monitoring (Ames;Eyetone) and fortnightly estimations of glycosylated haemoglobin. After 6 weeks on each diet, morning metabolic profiles, and 24-hour capillary blood and urinary glucose measurements were taken at home. The levels of blood glucose and b-hydroxybutyrate from the morning profiles, and the capillary blood and urinary glucose measurements from the 24-hour profiles were all lower on the unrefined diet. Mean blood glucose levels (mmo1/L±SEM) were; fasting 6.5±1.3 (U), 8.5±2.3 (R), peak (post breakfast) 13±2.6 (U), 17.3±1.6 (R), midday 6.2±0.7 (U),12.14 ± 1.2* (R). Mean 24-hour urinary glucose was; 14.4±5 gm (U) 53.8±21.7 gm (R)*. The use of whole foods high in dietary fibre can improve glycaemic control of diabetic children on liberal carbohydrate diets.
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pediatric, allergy, immunology, cardiology, endocrinology, epidemiology, public health, fetus, pregnancy, gasteroenterology, genetics, hematology, oncology, infectious disease, neonatology, nephrology, neurology, nutrition, pulmonology, rheumatology , Pediatric Research, PR, Pediatr Res, nature journals, nature publishing group
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