Extranodal Marginal Zone B-cell Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma of Cecum Presenting as Bright Red Bleed per Rectum—A Case Report with Review of Literature

Introduction Primary colorectal lymphomas are particularly rare and contribute to 0.2% of all colorectal malignancies. Gastroentrointestinal (GI) tract is most commonly a secondary involvement site for non-Hodgkin’s lymphoma (NHL). Primary NHL of GI tract are very rare, constituting about 1–4% of all GI tract malignancies. In GI tract, two-thirds of all cases occur in stomach followed by small intestine (9%). Clinical presentation depends upon the site of involvement. Pain, loss of appetite, and weight loss are the most common symptoms, while bleeding occurs more with gastric involvement. Case Report We present a case of a female presenting as bright red bleed per rectum who was found to have a cecal mass, subsequently diagnosed as extranodal marginal zone B-cell mucosa-associated lymphoid tissue lymphoma with extensive plasma cell differentiation. Conclusion The diagnosis may be challenging, but a solitary extranodal plasmacytoma and multiple myeloma must be excluded in all such cases.