Gilles Goetz - Pfizer(^ Pfizer Inc. | 人才画像

基本信息

Career Trajectory

Bio

Gilles Goetz currently works in the Hit Discovery and Optimization department at Pfizer. Gilles does research in Molecular Properties and Compound Quality. Working towards effective characterization of lipophilicity (SFLOGD-ELOGD) Solubility, Chemical Stability, Polarity (EPSA), aggregation and more.

Research Interests

Papers共 45 篇Author StatisticsCo-AuthorSimilar Experts

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Steering New Drug Discovery Campaigns: Permeability, Solubility, and Physicochemical Properties in the Bro5 Chemical Space

Giulia Caron,Jan Kihlberg,Gilles Goetz,Ekaterina Ratkova,Vasanthanathan Poongavanam,Giuseppe Ermondi

ACS Medicinal Chemistry Letters（2021）

Cited57Views0WOSBibtex

Updating the Portfolio of Physicochemical Descriptors Related to Permeability in the Beyond the Rule of 5 Chemical Space

Giuseppe Ermondi,Maura Vallaro,Gilles Goetz,Marina Shalaeva,Giulia Caron

European Journal of Pharmaceutical Sciences（2020）

Cited39Views0WOSBibtex

Entry of Therapeutics into the Brain: Influence of Exposed Polarity Calculated in Silico and Measured in Vitro by Supercritical Fluid Chromatography

Giacomo Russo,Francesco Barbato,Lucia Grumetto,Laurence Philippe,Frederic Lynen,Gilles H. Goetz

International Journal of Pharmaceutics (2019): 294-305

Cited11Views0WOSBibtex

Experimental Lipophilicity for Beyond Rule of 5 Compounds

Giuseppe Ermondi,Maura Vallaro,Gilles Goetz,Marina Shalaeva,Giulia Caron

Future Drug Discoveryno. 1 (2019)

Cited26Views0Bibtex

Leveraging Chromatography Based Physicochemical Properties for Efficient Drug Design

Gilles H. Goetz,Marina Shalaeva

ADMET & DMPK（2018）

Cited20Views0Bibtex

Physical Chemical Properties for Drug Design in Beyond Rule-of-Five Chemical Space

Marina Shalaeva,Gilles Goetz,Laurence Philippe

2018 Medicinal Chemistry Reviews Medicinal Chemistry Reviewspp.421-438, (2018)

Cited2Views0Bibtex

Determining Molecular Properties with Differential Mobility Spectrometry and Machine Learning

Stephen W. C. Walker,Ahdia Anwar,Jarrod M. Psutka,Jeff Crouse,Chang Liu,J. C. Yves Le Blanc,Justin Montgomery,Gilles H. Goetz,John S. Janiszewski,J. Larry Campbell,W. Scott Hopkins

Nature Communications（2018）

Cited32Views0WOSNATUREBibtex

EPSA: A Novel Supercritical Fluid Chromatography Technique Enabling the Design of Permeable Cyclic Peptides

Gilles H. Goetz,Laurence Philippe,Michael J. Shapiro

Journal of Chromatography & Separation Techniques（2018）

Cited114Views0WOSBibtex

114

Comparative Pharmacokinetic Profile of Cyclosporine (csa) with a Decapeptide and a Linear Analogue

David A. Price,Heather Eng,Kathleen A. Farley,Gilles H. Goetz,Yong Huang,Zhaodong Jiao,Amit S. Kalgutkar,Natasha M. Kablaoui,Bhagyashree Khunte,Spiros Liras,Chris Limberakis,Alan M. Mathiowetz,Roger B. Ruggeri,Jun-Min Quan,Zhen Yang

Organic & Biomolecular Chemistry（2017）

Cited22Views0WOSBibtex

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