First experimental validation of silicon-based sensors for monitoring ultra-high dose rate electron beams

Elisabetta Medina, Arianna Ferro, Mohammad Abujami, Aurora Camperi, Matteo Centis Vignali, Emanuele Data,Damiano Del Sarto, Umberto Deut,Fabio Di Martino, Mohammad Fadavi Mazinani, Marco Ferrero, Veronica Ferrero, Simona Giordanengo, Oscar A. Marti Villarreal, Mohammad Amin Hosseini,Felix Mas Milian, Luigi Masturzo,Diango M. Montalvan Olivares, Marco Montefiori, Giovanni Paternoster, Jake Harold Pensavalle,Valentina Sola,Roberto Cirio,Roberto Sacchi,Anna Vignati

FRONTIERS IN PHYSICS(2024)

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摘要
Monitoring Ultra-High Dose Rate (UHDR) beams is one of the multiple challenges posed by the emergent FLASH radiotherapy. Technologies (i.e., gas-filled ionization chambers) nowadays used in conventional radiotherapy are no longer effective when applied to UHDR regimes, due to the recombination effect they are affected by, and the time required to collect charges. Exploiting the expertise in the field of silicon sensors' applications into clinics, the medical physics group of the University and INFN Torino is investigating thin silicon sensors as possible candidates for UHDR beam monitoring, exploiting their excellent spatial resolution and well-developed technology. Silicon sensors of 30 and 45 mu m active thicknesses and 0.25, 1 and 2 mm2 active areas were tested at the SIT ElectronFlash machine (CPFR, Pisa) on 9 MeV electron beams, featuring a pulse duration of 4 mu s, a frequency of 1 Hz, and a dose-per-pulse ranging from 1.62 to 10.22 Gy/pulse. The silicon sensors were positioned at the exit of the ElectronFlash applicator, after a solid water build-up slab, and were readout both with an oscilloscope and with a multi-channel front-end readout chip (TERA08). A response linearity extending beyond 10 Gy/pulse was demonstrated by comparison with a reference dosimeter (FlashDiamond), thus fulfilling the first requirement of a potential application in UHDR beam monitoring.
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关键词
FLASH radiotherapy,ultra-high dose rate electron beams,beam monitoring,silicon sensors,TERA chip
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