基于环介导等温扩增技术的即时检测在检验医学中的应用
Chinese Journal of Laboratory Medicine(2021)
Abstract
伴随医学进步,操作简单、反应快速且无设备和专业技术人员依赖的即时检测(POCT)有望实现对患者进行连续监测、诊断、管理和筛查,是体外诊断行业的重要发展方向。结合新技术原理,在提高灵敏度、特异性的前提下进一步实现定性至精确定量的转变是POCT发展的必然。在POCT平台开发过程中,具有高效扩增特性及简单、快速且低成本特点的环介导等温扩增(LAMP)技术扮演着越来越重要的角色。本文概述了LAMP技术作用机制及基于LAMP技术开发POCT平台的研究进展和临床应用,总结了目前基于LAMP技术的POCT平台存在的不足及未来发展方向。
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Key words
Point-of-care testing,Disease,Diagnosis
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