Ⅰ型和Ⅱ型子宫内膜癌患者中医证候差异性初探
Journal of Beijing University of Traditional Chinese Medicine（2020）
Abstract
目的 探讨Ⅰ型和Ⅱ型子宫内膜癌(EC)患者中医证候分布规律及其在年龄、子宫内膜厚度、体重指数(BMI)等方面的差异,以期为中医药防治EC提供理论依据.方法 回顾性分析87例EC患者的临床病例资料,归纳并比较Ⅰ型和Ⅱ型EC患者中医证候分布、年龄、子宫内膜厚度、BMI等方面的分布差异.结果 Ⅰ型EC患者67例,以脾肾阳虚证为主,Ⅱ型EC患者20例,以肝肾阴虚证为主,组间比较差异有统计学意义(P<0.05).Ⅰ型EC患者平均年龄小于Ⅱ型EC患者,可见于育龄期及非育龄期,Ⅱ型EC患者均为非育龄期,组间比较差异有统计学意义(P<0.05);Ⅰ型EC患者术前内膜厚度大于Ⅱ型EC患者,组间比较差异有统计学意义(P<0.05);Ⅰ型EC患者超重比例高于Ⅱ型EC患者,组间比较差异有统计学意义(P<0.05);Ⅰ型EC患者合并高血压、糖尿病、血脂异常人数多于Ⅱ型EC患者,但组间比较差异无统计学意义(P>0.05).结论 Ⅰ型EC患者以脾肾阳虚证为主,Ⅱ型EC以肝肾阴虚证为主,二者在年龄、子宫内膜厚度、BMI等方面分布具有差异性.临床应根据EC患者具体情况辨证施治,以更好地发挥中医药在防治EC方面的优势.
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