大肠癌术前淋巴结转移列线图预测模型的建立和验证
Journal of Youjiang Medical University for Nationalities（2020）
Abstract
目的 建立并验证大肠癌患者术前淋巴结转移的列线图预测模型.方法 根据大肠癌术后病理结果,将316例患者分为淋巴结转移阳性组(n=160)和阴性组(n=156),多因素Logistic回归分析大肠癌淋巴结转移相关的预测因素,R软件绘制列线图并进行内部验证.结果 列线图包含肿瘤分化程度、血清癌胚抗原(CEA)水平、糖尿病以及CT报告的淋巴结转移状态4个预测因子,该模型具有较好的区分度和校准度,ROC曲线下面积(AUC)为0.865(95％CI:0.826～0.904).结论 结合影像学和临床病理特点开发了一个简便、高效的列线图预测模型,临床医生可用于术前评估大肠癌患者有无淋巴结转移.
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