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Chemical, Biochemical, Pharmacokinetic, and Biological Properties of L-680,833: a Potent, Orally Active Monocyclic Beta-Lactam Inhibitor of Human Polymorphonuclear Leukocyte Elastase.

JB DOHERTY,SK SHAH,PE FINKE,CP DORN,WK HAGMANN,JJ HALE,AL KISSINGER,KR THOMPSON,K BRAUSE,GO CHANDLER,WB KNIGHT,AL MAYCOCK, BM AHSE,H WESTON,P GALE,RA MUMFORD,OF ANDERSEN,HR WILLIAMS, TE NOLAN, DL FRANKENFIELD,D UNDERWOOD,KP VYAS,PH KARI,ME DAHLGREN, J MAO,DS FLETCHER,PS DELLEA,KM HAND,DG OSINGA,LB PETERSON,DT WILLIAMS,JM METZGER,RJ BONNEY,JL HUMES, SP PACHOLOK,WA HANLON, E OPAS, J STOLK,P DAVIES

Proceedings of the National Academy of Sciences of the United States of America（1993）

Cited 55|Views29
Key words
SYNTHETIC ELASTASE INHIBITORS,LUNG INJURY,FIBRINOGEN CLEAVAGE
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