Homologous Recombination-Dna Damage Response Defects Increase TMB and Neoantigen Load, but Not Effector T Cell Density and Clonal Diversity in Pancreatic Cancer
Experimental Hematology & Oncology（2025）
Key words
Pancreatic ductal adenocarcinoma (PDAC),Homologous recombination-DNA damage response defects,Tumor mutation burden (TMB),T cell infiltration,T cell clonal diversity,Immune checkpoint inhibitors
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