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Identifying Molecular Properties of Ataxin-2 Inhibitors for Spinocerebellar Ataxia Type 2 Utilizing High-Throughput Screening and Machine Learning

Smita Sahay, Jingran Wen,Daniel R Scoles,Anton Simeonov, Thomas S Dexheimer,Ajit Jadhav,Stephen C Kales,Hongmao Sun, Stefan M Pulst,Julio C Facelli, David E Jones

Biology(2025)

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关键词
spinocerebellar ataxia type 2,<i>ATXN2</i> gene,high-throughput screening,machine learning,small molecule drug discovery
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