Structure-Guided Design of ISOX-DUAL-Based Degraders Targeting BRD4 and CBP/EP300: A Case of Degrader Collapse.

Anthony K Edmonds, Dimitrios-Ilias Balourdas, Graham P Marsh, Robert Felix, Bradley Brasher, Jeff Cooper, Cari Graber-Feesl,Madhu Kollareddy, Karim Malik,Helen Stewart, Timothy J T Chevassut, Ella Lineham,Simon Morley,Oleg Fedorov, James Bennett, Mohan B Rajasekaran, Samuel Ojeda, Drew A Harrison,Christopher J Ott,Andreas C Joerger, Hannah J Maple,John Spencer

Journal of medicinal chemistry（2025）

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