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Microfluidic Optimization of PEI-Lipid Hybrid Nanoparticles for Efficient DNA Delivery and Transgene Expression

Mahboubeh Hosseini-Kharat,Anthony Wignall, Zelalem A Mekonnen, Ben S-Y Ung, Bradley Chereda,Kristen E Bremmell,Branka Grubor-Bauk,Clive A Prestidge

Pharmaceutics(2025)

Cited 0|Views3
Key words
lipid nanoparticles (LNPs),polyethyleneimine (PEI),DNA delivery,microfluidic mixing,transgene expression,luciferase assays,GFP expression,lipid-polymer hybrid systems,gene therapy
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