Design and Development of Highly Conserved, HLA-promiscuous T Cell Multiepitope Vaccines Against Human Visceral Leishmaniasis

Aline Silva Barreto,Mariana Nobre Farias de Franca, Tatiana Leão Dos Santos Dos Reis, Joao Antonio Barbosa Martins Silva, Priscila Lima Dos Santos, Fabrícia Alvisi de Oliveira,Angela Maria da Silva,Lucas Sousa Magalhaes, Danielle Angst Secco, Maria Aiza Fontes Andrade,Luís Cristóvão Porto,Daniela Santoro Rosa, Rafael Ciro Marques Cavalcante, Cristiane Bani Corrêa,John Sidney,Alessandro Sette,Roque Pacheco de Almeida, Clarisa Beatriz Palatnik-de-Sousa

Frontiers in immunology（2025）

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Key words

multiepitope based vaccines,leishmaniosis,visceral leishmaniosis,HLA class I and class II promiscuous epitopes,Leishmania conserved antigens

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