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A Comprehensive Strategy for the Development of a Multi-Epitope Vaccine Targeting Treponema Pallidum, Utilizing Heat Shock Proteins, Encompassing the Entire Process from Vaccine Design to in Vitro Evaluation of Immunogenicity

Jing Jiang, Linglan Xu, Xuefeng Wang,Ming Wang, Youde Cao,Ranhui Li, Kang Zheng, Xian Wu

Frontiers in microbiology(2025)

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Key words
Treponema pallidum,heat shock protein,reverse vaccinology,immunoinformatic,subtractive proteomics,immune stimulation
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