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ADT-1004: a First-in-class, Oral Pan-Ras Inhibitor with Robust Antitumor Activity in Preclinical Models of Pancreatic Ductal Adenocarcinoma

Dhana Sekhar Reddy Bandi,Ganji Purnachandra Nagaraju, Sujith Sarvesh,Julienne L. Carstens,Jeremy B. Foote,Emily C. Graff, Yu-Hua D Fang,Adam B. Keeton, Xi Chen,Jacob Valiyaveettil, Kristy L. Berry,Sejong Bae, Mehmet Akce, Greg Gorman, Karina J. Yoon,Upender Manne,Michael R. Boyd,Donald J. Buchsbaum,Asfar S. Azmi, Yulia Y. Maxuitenko,Gary A. Piazza,Bassel F. El-Rayes

Molecular Cancer（2025）

Cited 0|Views3
Key words
Pancreatic ductal adenocarcinoma,pan-RAS inhibitor,Tumor immune microenvironment,KRAS,RAS-driven malignancies
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