Integrated UPLC-ESI-MS/MS, Network Pharmacology, and Transcriptomics to Reveal the Material Basis and Mechanism of Schisandra Chinensis Fruit Mixture Against Diabetic Nephropathy

Yuan-Yuan Deng, Xin-Yu Ma,Peng-Fei He,Zheng Luo,Ni Tian,Shao-Ning Dong,Sai Zhang, Jian Pan, Peng-Wei Miao, Xiang-Jun Liu, Cui Chen, Peng-Yu Zhu, Bo Pang, Jing Wang, Li-Yang Zheng, Xin-Kun Zhang,Min-Ying Zhang,Mian-Zhi Zhang

Frontiers in immunology（2025）

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Key words

network pharmacology,diabetic nephropathy,Schisandra chinensis Fruit Mixture,JAK2/ATAT3 signalling pathway,inflammatory response,apoptosis

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