Single-molecule M6a Detection Empowered by Endogenous Labeling Unveils Complexities Across RNA Isoforms

Wenbing Guo, Zhijun Ren, Xiang Huang, Jiayin Liu, Jingwen Shao, Xiaojun Ma, Chuanchuan Wei,Yixian Cun, Jialiang He, Jie Zhang, Zehong Wu,Yang Guo, Zijun Zhang, Zhengming Feng, Jianbo He,Jinkai Wang

Molecular Cell（2025）

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关键词

N6-methyadenosine,RNA isoform,Oxford Nanopore direct RNA sequencing,deep residual neural network,isoform-specific,epithelial-mesenchymal transition,alternative promoter

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