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Association of Prior PARP Inhibitor Exposure with Clinical Outcomes after 177Lu-Psma-617 in Men with Castration-resistant Prostate Cancer and Mutations in DNA Homologous Recombination Repair Genes

Ruben Raychaudhuri,Abuzar Moradi Tuchayi, Soon Khai Low,Ali T. Arafa,Laura S. Graham,Roman Gulati,Colin C. Pritchard,Robert B. Montgomery,Michael C. Haffner,Peter S. Nelson,Evan Y. Yu,Jessica E. Hawley,Heather H. Cheng,George Mo,Delphine L. Chen,Emmanuel S. Antonarakis, Deepak Kilari,Thomas A. Hope,Amir Iravani,Michael T. Schweizer

European Urology Oncology（2025）

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Key words
177Lu-PSMA-617,ATM gene,BRCA2 gene,DNA damage repair,Metastatic prostate cancer,Prostate-specific membrane antigen,PARP inhibitor
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