EDF1 Accelerates Ganglioside GD3 Accumulation to Boost CD52-mediated CD8+ T Cell Dysfunction in Neuroblastoma.

Di Li, Meng Li, Zhenjian Zhuo,Huiqin Guo, Weixin Zhang, Yile Xu,Hai-Yun Wang, Jiabin Liu,Huimin Xia,Huiran Lin,Jue Tang,Jing He,Lei Miao

Journal of Experimental & Clinical Cancer Research（2025）

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Key words

EDF1,Neuroblastoma,CD8+ T cell dysfunction,LacCer metabolism,GD3

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