Mechano-electrical Transduction Components TMC1-CIB2 Undergo a Ca2+-induced Conformational Change Linked to Hearing Loss

Shaoxuan Wu, Lin, Qiaoyu Hu, Xuebo Yao,Hongyang Wang, Shuang Liu, Qingling Liu,Yuehui Xi, Yuzhe Lin, Jianqiao Gong,Ruixing Hu, Wei Zhan, Yi Luo,Guang He, Zhijun Liu,Wei Xiong,Qiuju Wang,Zhigang Xu,Fang Bai,Qing Lu

Developmental Cell（2025）

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Key words

hearing loss,genetic heterogeneity,mechano-electrical transduction,EF-hand protein,calcium

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