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Pharmacological Modulation of Sigma-1 Receptor Ameliorates Pathological Neuroinflammation in Rats with Diabetic Neuropathic Pain Via the AKT/GSK-3β/NF-κB Pathway

Yuyu An, Shanshan Cao, Leilei Shi,Yuhan Zhang,Xin Wang, Shiyu Yuan,Yongheng Shi,Bin Wang,Jiping Liu,Chao-jun Han

BRAIN RESEARCH BULLETIN（2025）

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Key words
Sigma-1 receptor,Dorsal root ganglia,Neuroinflammation,Microglia-like cell,PRE-084,GSK-3 beta,Lipopolysaccharide (LPS)
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