Enhanced BBB Penetration and Microglia-Targeting Nanomodulator for the Two-Pronged Modulation of Chronically Activated Microglia-Mediated Neuroinflammation in Alzheimer’s Disease

Ya Wei, Xue Xia,Xiaorong Wang, Wenqin Yang,Siqin He,Lulu Wang, Yongke Chen,Yang Zhou,Feng Chen,Hanmei Li,Fu Peng,Guobo Li,Zheng Xu, Jintao Fu,Huile Gao

Acta Pharmaceutica Sinica B（2025）

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Blood‒brain barrier penetration,Microglial targeting,Microglial modulation,Chronic neuroinflammation,Alzheimer’s disease,Immunotherapy,TREM2,Resveratrol

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