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Integrated Analysis of Bioinformatics, Mendelian Randomization, and Experimental Validation Reveals Novel Diagnostic and Therapeutic Targets for Osteoarthritis: Progesterone As a Potential Therapeutic Agent

Ziyu Weng, Chenzhong Wang,Bo Liu,Yi Yang,Yueqi Zhang,Chi Zhang

Journal of Orthopaedic Surgery and Research(2025)

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Key words
Osteoarthritis,Biomarker,Machine learning,Artificial neural networks,IRAK3,Drug prediction,Molecular docking,Progesterone,Mendelian randomization
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