Opportunities for More Tailored Approaches to Genotoxicity Testing and Carcinogenicity Strategy for Oligonucleotide Therapeutics: Outcome of an Industry Survey

Joel D. Parry, Tod A. Harper,Patrik Andersson, Joanne M. Elloway, Natalie S. Holman,William E. Achanzar,Anthony Lynch,Yann Tessier, Meredith Crosby, Eike Floettmann, Marie Coeffet,Melanie Guerard, Nicole H. P. Cnubben, Onyi N. Irrechukwu, Olivier Wattrelos, Yi Yang

NUCLEIC ACID THERAPEUTICS（2025）

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Key words

genotoxicity,carcinogenicity,oligonucleotide,EFPIA,survey,ICH S2(R1)

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