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TIFA Renders Intestinal Epithelial Cells Responsive to Microbial ADP-heptose and Drives Colonic Inflammation in Mice

Lena Erkert,Barbara Ruder, Melanie Kabisch,Reyes Gamez Belmonte,Jay V. Patankar,Miguel Gonzalez Acera, Lena Schödel,Mircea T. Chiriac, Roodline Cineus, Stylianos Gnafakis,Tamara Leupold,Oana-Maria Thoma,Iris Stolzer, Astrid Taut,Veronika Thonn,Sebastian Zundler,Claudia Günther,Andreas Diefenbach,Anja A. Kühl,Ahmed N. Hegazy

Mucosal Immunology（2025）

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Key words

TIFA,Intestinal epithelium,IBD,ADP-heptose,IL-22

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