Transcriptomics Analysis Reveals Potential Mechanisms Underlying Mitochondrial Dysfunction and T Cell Exhaustion in Astronauts’ Blood Cells in Space

Maria Moreno-Villanueva, Luis E. Jimenez-Chavez,Stephanie Krieger, Liang-Hao Ding, Ye Zhang, Adriana Babiak-Vazquez,Mark Berres, Sandra Splinter,Kristen E. Pauken, Brian C. Schaefer,Brian E. Crucian,Honglu Wu

FRONTIERS IN IMMUNOLOGY（2025）

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Key words

spaceflight,transcriptomics,astronauts’ health,mitochondria,immune dysfunction,telomere lengthening

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