S1PR3 in Hippocampal Neurons Improves Synaptic Plasticity and Decreases Depressive Behavior Via Downregulation of RhoA/ROCK1

Huiqin Liu,Shuhua Chen,Hong Xiang,Jie Xiao,Shaoli Zhao, Xiao Zhang, Zhihao Shu,Jing Zhang, Jie Ouyang, Quanjun Liu, Qisheng Quan, Jianing Fan,Peng Gao, Xinru Zheng,Alex F. Chen,Hongwei Lu

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY（2025）

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Key words

S1PR3,RhoA,Depression,Synaptic plasticity,Hippocampus

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