Highly Efficient and Universal Degradation of PD-L1 Via Mitochondrial Oxidative Stress Evoked by Cationic AIE-Active Photosensitizers for Cancer Immunotherapy

Jiazhe Liu,Ruoyao Zhang, Yixuan Bao, Yijun Chen, Wenfang Zheng, Jianing Yuan, Zhuomiao Zhang,Pu Chen,Meiju Ji,Yangyang Cheng,Peng Hou,Dongfeng Dang,Dan Ding,Chao Chen

ADVANCED FUNCTIONAL MATERIALS（2025）

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Key words

aggregation-induced emission,immunotherapy,mitochondrial targeting,PD-L1 degradation,photosensitizers

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