Optimization and Validation of an Ultra-Performance Liquid Chromatography with Quadrupole Detector Mass Spectrometry Quantification Method for the Simultaneous Detection of Tazarotene and Tazarotenic Acid in Porcine Skin: an in Vitro Study
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES(2025)
关键词
tazarotene,tazarotenic acid,hand osteoarthritis,quadrupole detector mass spectrometry (QDa),design of experiments (DoE),transdermal,bioanalytical techniques
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