Ectopic Expression of DNMT3L in Human Trophoblast Stem Cells Restores Features of the Placental Methylome

Georgia Lea, Paula Doria-Borrell, Ana Ferrero-Micó, Anakha Varma,Claire Simon, Holly Anderson,Laura Biggins,Katrien De Clercq,Simon Andrews,Kathy K. Niakan,Lenka Gahurova,Naomi McGovern,Vicente Pérez-García,Courtney W. Hanna

Cell Stem Cell（2025）

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DNMT3L,DNA methylation,placenta,human trophoblast stem cells,epigenetics,histone modifications,differentiation,syncytiotrophoblast,partially methylated domains

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