The Effect of Zopiclone Co-Administration on Sertraline Initial Dosage Optimization in Pediatric Major Depressive Disorder Patients Based on Model-Informed Precision Dosing

Xiao Chen, Ke Hu,Hao-Zhe Shi,Su-Mei He, Yang, Chao-Wen Yang, Yue Zhang, Xue Tian, Ye Li, Yu-Hang Gao, Wen-Yi Xu,Cun Zhang,Dong-Dong Wang

FRONTIERS IN PHARMACOLOGY（2025）

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zopiclone,sertraline,initial dosage optimization,pediatric major depressive disorder,model-informed precision dosing,drug-drug interaction

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