The Effect of HLA Genotype on Disease Onset and Severity in CTLA-4 Insufficiency

Sara Posadas-Cantera,Noriko Mitsuiki,Florian Emmerich,Virginia Patino, Hanns-Martin Lorenz,Olaf Neth,Ingunn Dybedal,Kjetil Tasken, Alejandro A. Schaffer,Bodo Grimbacher,Laura Gamez-Diaz

FRONTIERS IN IMMUNOLOGY（2025）

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cytotoxic T-lymphocyte antigen 4 (CTLA-4),immune dysregulation,inborn errors of immunity (IEI),disease modifiers,human leukocyte antigen (HLA),genetic linkage analysis

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