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Metabolic Reprogramming and Macrophage Expansion Define ACPA-negative Rheumatoid Arthritis: Insights from Single-Cell RNA Sequencing

Yafeng Jiang,Zhaolan Hu,Roujie Huang, Kaying Ho, Pengfei Wang,Jin Kang

FRONTIERS IN IMMUNOLOGY（2025）

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Key words
rheumatoid arthritis,single-cell RNA sequencing,ACPA,synovial macrophage,beta-alanine and glutathione metabolism
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