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Altered Chromatin Landscape and 3D Interactions Associated with Primary Constitutional MLH1 Epimutations

Paula Climent-Cantó,Marc Subirana-Granés,Mireia Ramos-Rodríguez,Estela Dámaso,Fátima Marín, Covadonga Vara,Beatriz Pérez-González, Helena Raurell,Elisabet Munté,José Luis Soto, Ángel Alonso,GiWon Shin,Hanlee Ji,Megan Hitchins,Gabriel Capellá,Lorenzo Pasquali,Marta Pineda

Clinical Epigenetics（2024）

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Key words
Lynch syndrome,Constitutional MLH1 epimutation,MLH1 promoter methylation,3D interactions,Chromatin structure,Cis-regulatory regions
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