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Identification of Novel CNS-Tropic AAVs Using in Vitro Binding to Candidate Receptors Combined with in Vivo Screening, Generative AI, and Structural Modeling

John Reece-Hoyes, Jackson Lee, Jie Tan, Estrella Lopez-Gordo, Caroline Curll, Fion Chan,Sri Siripurapu, Stephanie Malyszka,Kimberly Le,Allegra Fieldsend, Haley Knight, Paul Freeman, Matt Bennett, Esther Aribilola, Ramin Kamran Sami, Shahrzad Parker, Jordan Shufro, Graham Lilley,Bryan Mastis,Roberto Calcedo,Matt Edwards, Sherry Cao,Charles F. Albright

MOLECULAR THERAPY(2024)

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