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Molecular Profiling Identifies CD49d and CD79b As Predictive Markers for Acquired Acalabrutinib Resistance in Patients with Chronic Lymphocytic Leukemia

Elena Bibikova, Sara Parsa,Muskan Floren, Brian Law,Tracy Clevenger,Jean Cheung,Gary De Jesus, Kathleen Burke,Michael Gulrajani,Kyoko Yamaguchi, Phuong Do,Brian Dougherty,David Whitston,Graham Brock,Veerendra Munugalavadla,Melanie M. Frigault,Tanja N. Hartmann,John C. Byrd,Richard R. Furman,Jennifer R. Brown,Todd Covey,Andrew Mortlock

HEMATOLOGICAL ONCOLOGY（2025）

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关键词
BTK inhibitor,drug resistance,ITGA4,lymphocytosis,tumor microenvironment,VLA-4
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