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MiR-495 Reverses in the Mechanical Unloading, Random Rotating and Aging Induced Muscle Atrophy Via Targeting MyoD and Inactivating the Myostatin/TGF-β/Smad3 Axis

Chenyan Zhang, Yile Tian,Xinli Liu,Xuezhou Yang,Shanfeng Jiang,Ge Zhang,Changqing Yang,Wenjing Liu,Weihong Guo, Wenzhe Zhao,Dachuan Yin

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS（2025）

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Key words
Mechanical unloading,Aging-associated muscle atrophy,MiR-495,MyoD,Myostatin/TGF-beta/Smad3 axis
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