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Exploratory Study of Extracellular Matrix Biomarkers for Non-Invasive Liver Fibrosis Staging: A Machine Learning Approach with XGBoost and Explainable AI

Valeria Carnazzo,Stefano Pignalosa, Marzia Tagliaferro,Laura Gragnani,Anna Linda Zignego, Cosimo Racco,Luigi Di Biase,Valerio Basile,Gian Ludovico Rapaccini,Riccardo Di Santo,Benedetta Niccolini,Mariapaola Marino,Marco De Spirito,Guido Gigante,Gabriele Ciasca,Umberto Basile

CLINICAL BIOCHEMISTRY（2025）

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关键词
Biomarkers,ECM,Liver fibrosis,HCV,Collagen-IV,Collagen-III N -peptide,Machine learning,XGBoost,Explainable AI
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